Ahhhh… excellent question, these! I tend to play the slightly modified “shag means make out” version, which leads me to…
Marry McSteamy (or, if I can’t, I want him to get back with Lexie so she can!)
Make out with Avery (oh, those eyes. THOSE EYES).
Throw McDreamy off a cliff. (Seriously, he is not all that dreamy. And also, he is frequently a sanctimonious jerk to Meredith et al).